Giving the Midlands’ Most Vulnerable Animals a Second Chance
A no-kill, foster-based rescue serving Lexington and the South Carolina Midlands. We give kittens, puppies, pregnant and nursing animals, special-needs pets, and community cats the care, safety, and second chance they deserve.
Our Mission
In service of domestic animals in South Carolina, Frisky Business Rescue is a no-kill rescue that provides vital resources such as veterinary care, birthing assistance, medication, and rehoming or safe release (TNR) to the most vulnerable animals in the region. We specialize in animals with special circumstances that come from various backgrounds, including animal hoarding and abusive situations but primarily focus on vulnerable kittens, puppies, and pregnant/nursing dogs and cats. Before rehoming, we carefully screen new potential families to ensure the needs of our animals can be met and that new homes will become furever homes.
What Makes Us Different
Foster & Home-Based Care
Our rescue facility is located beside our home, allowing us to give every animal plenty of individualized attention. Dogs are regularly brought into the home environment, where we evaluate how they handle everyday life, household routines, and other pets, giving us a much better understanding of what adopters can expect. Cats, once through quarantine, are acclimated to a cage-free environment and introduced to other cats, with dogs tested upon request. This helps them become comfortable and confident before meet-and-greets, making the transition to adoption smoother for everyone.
Intentional Rescue
We focus on animals who are especially vulnerable in a traditional shelter environment, including small dogs who can become overwhelmed, XL dogs who need more space, dogs who require grooming, litters of kittens, and senior animals. We prioritize those who benefit most from the extra time, space, specialized placement, and individualized care a foster-based rescue can provide.
Community Cats & TNR
We trap, neuter, and return or safely release community cats, helping reduce overpopulation, prevent unnecessary suffering, and stabilize local colonies through humane population management.
Our Impact
The difference our fosters, volunteers, and supporters make.
723
Animals helped
448
Adopted into homes
98
Community cats in TNR
2022
Rescuing since
Meet Our Animals
Our adoptable cats and dogs are looking for their furever homes. Because we’re foster-based, meet-and-greets are by appointment and adoption applications must be completed prior for safety reasons.
New to adopting? See how our adoption process works.
Our Story
A 501(c)(3) nonprofit since 2022, Frisky Business Rescue serves Lexington, Richland, and Orangeburg counties — focusing on the animals that need the most help.
Follow Along on Facebook
See our newest rescues, urgent needs, and happy tails as they happen.
Ways to Help
Adopt
Give a rescued animal their furever home.
Foster
Open your home and save two lives at once.
Volunteer
Give time — transport, events, TNR, or photos.
Donate
Fuel vet care for the next animal we rescue.